Human placenta cells die after BPA exposure

Environmental Health News: "Human placenta cells die after BPA exposure.
Feb 02, 2010

Benachour, N and A Aris. Toxic effects of low doses of Bisphenol-A on human placental cells. Toxicology and Applied Pharmacology doi:10.1016/j.taap.2009.09.005.

Synopsis by Wendy Hessler and Heather Patisaul, Ph.D.
Exposure to very low concentrations of the plastic monomer bisphenol A (BPA) causes cellular damage and death in cultured human placenta cells, researchers report. The doses used for this study are similar to blood levels found in pregnant women. A particularly worrying finding is that effects were most pronounced at the lowest – rather than the highest – concentrations of BPA indicating that placental development could be particularly sensitive to BPA exposure

Damage to the placenta can induce a range of adverse pregnancy outcomes including premature birth, preeclampsia or even pregnancy loss.

It is not known if exposure to BPA is associated with adverse pregnancy outcomes in humans."